Table 2.

Frequencies of IgG, IgA and IgE responses in sera of COVID-19 patients collected > 14 DPS, %

Antigen	Mild, %			Moderate, %			Severe, %			Total, %
	IgG	IgA	IgE	IgG	IgA	IgE	IgG	IgA	IgE	IgG	IgA	IgE
Full-lenght proteins or subunits
SFL3	94.7	16.7	66.7	100	38.5	92.3	100	54.5	90	97.3	30.1	79.7
SFL	97.4	25	12.1	100	42.3	50	100	54.5	60	98.7	35.6	33.3
SRBD	92.1	22.2	0	100	42.3	3.85	100	63.6	10	96	35.6	2.9
S1sub	89.5	22.2	0	100	42.3	34.6	100	63.6	20	94.7	35.6	15.9
S2sub	100	25	3.03	100	42.3	19.2	100	54.5	20	100	35.6	11.6
NFL	94.7	19.4	66.7	100	46.2	96.2	100	45.5	100	97.3	32.9	82.6
MFL	84.2	13.9	0	100	30.8	23.1	100	45.5	0	92	24.7	8.7
Predicted epitopes or protein fragments
S1	5.26	0	0	7.69	0	0	27.3	0	0	9.33	0	0
S2	31.6	0	0	26.9	0	0	72.7	0	0	36	0	0
S3	26.3	0	0	26.9	0	0	54.5	0	0	30.7	0	0
S4	5.26	0	0	15.4	0	0	36.4	0	0	13.3	0	0
S5	34.2	0	0	23.1	0	0	36.4	0	0	30.7	0	0
S6	13.2	0	0	15.4	0	3.85	0	0	0	12	0	1.45
S7	42.1	2.78	15.2	69.2	0	34.6	90.9	0	30	58.7	1.37	24.6
S8	13.2	0	0	15.4	3.85	0	18.2	0	0	14.7	1.37	0
S9	28.9	0	0	26.9	0	0	45.5	0	0	30.7	0	0
S10	15.8	0	0	15.4	0	0	18.2	0	0	16	0	0
S11	0	0	0	7.69	0	7.69	18.2	0	0	5.33	0	2.9
M1	18.4	0	0	38.5	0	0	54.5	0	0	30.7	0	0
N1	28.9	0	0	30.8	3.85	0	54.5	0	0	33.3	1.37	0
N2	42.1	0	0	53.8	0	0	63.6	0	0	49.3	0	0
NSP1	36.8	0	0	15.4	0	0	36.4	0	0	29.3	0	0
NSP2	7.89	0	0	11.5	0	0	27.3	0	0	12	0	0
NSP3	2.63	0	ND	11.5	0	ND	9.09	0	ND	6.67	0	ND
NSP4	2.63	0	ND	3.85	0	ND	0	0	ND	2.67	0	ND
NSP5	31.6	0	ND	34.6	0	ND	45.5	0	ND	34.7	0	ND
ORF3b	2.63	0	ND	3.85	0	ND	18.2	0	ND	5.33	0	ND
ORF8	7.89	0	ND	7.69	0	ND	18.2	0	ND	9.33	0	ND
ORF8_1	0	0	ND	0	0	ND	0	0	ND	0	0	ND
ORF8_2	5.26	0	ND	15.4	0	ND	27.3	0	ND	12	0	ND