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. 2022 Apr 14;27(15):2001551. doi: 10.2807/1560-7917.ES.2022.27.15.2001551

Table 2. Unadjusted symptomatic secondary attack rates and odds ratios for secondary SARS-CoV-2 infection (probable and confirmed secondary cases), United Kingdom, January to March 2020 (n =440).

Variable levels SAR 95% CI OR 95% CI
Household
Household size 2 0.49 0.37–0.60 1.00 Reference value
3 0.41 0.30–0.51 0.62 0.26–1.53
4 0.32 0.22–0.42 0.36 0.15–0.90
≥ 5 0.25 0.13–0.37 0.23 0.07–0.71
Interactions
Sex Male → Male 0.37 0.26–0.48 1.00 Reference value
Male → Female 0.42 0.33–0.50 1.36 0.69–2.69
Female → Male 0.34 0.26–0.43 0.85 0.34–2.13
Female → Female 0.29 0.16–0.42 0.59 0.19–1.84
Comorbidities None → none 0.37 0.29–0.45 1.00
None → comorbidities 0.46 0.30–0.62 1.70 0.58–4.95
Comorbidities → none 0.36 0.25–0.47 0.95 0.39–2.29
Comorbidities → comorbidities 0.46 0.28–0.64 1.71 0.53–5.56
Characteristics of contact
Sex Male 0.36 0.29–0.43 1.00 Reference value
Female 0.38 0.31–0.45 1.15 0.68–1.94
Age group (years) < 18 0.30 0.21–0.39 0.62 0.28–1.38
18–34 0.37 0.28–0.47 1.00 Reference value
35–64 0.43 0.35–0.51 1.38 0.67–2.85
≥ 65 0.35 0.13–0.57 0.86 0.19–3.87
Characteristics of primary case
Sex Male 0.41 0.33–0.49 1.00 Reference value
Female 0.33 0.25–0.41 0.61 0.30–1.26
Age group (years) < 18 0.89 0.7–1.05 41.89 4.46–393.02
18–64 0.35 0.29–0.41 1.00
≥ 65 0.42 0.25–0.59 1.51 0.53–4.26
Hospital admission Without hospital admission 0.43 0.36–0.51 1.00 Reference value
With hospital admission 0.28 0.20–0.36 0.37 0.18–0.77
Cough sneezing Without cough/sneeze 0.32 0.19–0.46 1.00
With cough/sneeze 0.38 0.32–0.44 1.42 0.54–3.70
Overall 0.37 0.31–0.43 NA

CI: confidence interval; NA: not applicable; OR: odds ratio; SAR: secondary attack rate; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.