Table 1.

The 16 dysregulated preeclampsia associated genes by PFBS

Gene Name	Functions
ADMATS1	associated with various inflammatory process
ADM	vasodilation, angiogenesis, antimicrobial
ANGPTL4	angiogenesis, proliferation, migration, invasion
CNTF	survival factors for various neuronal cells
CXCL12	vasculogenic actions, regulate trophoblast function and uterine spiral artery remodeling
DDX10	embryogenesis, cellular growth and division
FGF5	embryonic development, cell growth and invasion; associated with hypertension
FILIP1L	angiogenesis activity, cell proliferation and migration
IGFBP5	suppress trophoblast cell migration and invasion in Preeclampsia
IL7R	Immune regulation
KCTD11	growth and proliferation
PAPPA	Inflammation, wound healing, associated with preeclampsia, female infertility.
PSG4	Immune regulation
RUNX1	an regulator of hematopoiesis in placenta, associated with preterm birth
SERPINE1	cellular differentiation, modulation of apoptosis and steroidogenesis, associated with preeclampsia
SNAI2	Focal adhesion, associated with placenta development and function and preeclampsia.