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. 2022 Mar 29;12:863655. doi: 10.3389/fonc.2022.863655

Table 4.

EPIC-26 summary score changes and proportions of patients with declines above the minimally important difference.

EPIC-26 1 mo 3mo 6mo 9mo 12 mo 18 mo 24mo 30 mo 36 mo 42mo 48mo 54mo 60 mo
Urinary domain
median =88
SD =12.4
Median change
(IOR)
-8 (-21, 0) 0 (-6, 4) 0 (-6, 4) 0 (-9, 4) -2 (-8, 4) 0 (-9, 4) -2 (-7, 4) 0 (-7, 6) 0 (-8, 6) 0 (-6, 6) 0 (-7, 4) 0 (-7, 6) -2 (-9, 4)
MID 6.2 points
Proportion with decline >MID 54.40% 24.70% 23.10% 29.10% 34.70% 29.10% 26.40% 25.90% 26.30% 24.00% 26.00% 31.00% 33.30%
Bowel domain
median =96
SD =8.5
Median change
(IQR)
-3 (-11, 0) 0 (-5, 3) 0 (-5, 2) 0 (-5, 2) 0 (-6, 2) 0 (-5, 3) 0 (-5, 3) 0 (-7, 3) 0 (-5, 3) 0 (-5, 2) 0 (-3, 3) 0 (-5, 2) 0 (-6, 2)
MID 4.2 points
Proportion with decline >MID 43.60% 27.30% 28.60% 29.00% 31.00% 28.20% 30.40% 26.50% 30.20% 25.00% 26.00% 25.00% 23.60%
Sexual domain
median =42
SD =26.9
Median change (IQR) -6(-19, -3) -2(-15, 3) -4(-16, 3) 0(-13, 6) -2(-14, 6) -2(-12, 8) -2(-13, 8) -2(-13, 6) -4(-13, 8) -7(-18, 5) -6(-19, 6) -6(-17, 3) 10(-23, -2)
MID 13.4 points
Proportion with decline >MID 36.50% 29.40% 27.90% 24.20% 25.10% 22.50% 24.90% 23.10% 29.10% 34.70% 35.40% 34.60% 37.70%