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. 2022 Apr 15;132(8):e151817. doi: 10.1172/JCI151817

Figure 4. Expression of senescence pathway and SASP effector genes in the spinal cords of mice of both sexes 6 months after sham or SNI surgery.

Figure 4

(A) Biological pathways leading to cellular senescence. (B) Expression of senescence pathway genes. (C) Expression of SASP effector genes. Bars in B and C represent mean ± SEM (n = 6–8 mice/surgery/sex; values shown are averages of 3 technical replicates) relative expression compared with the housekeeping gene, Gapdh, and normalized to the same-sex sham group. *P < 0.05, **P < 0.01, ***P < 0.001 compared with all other groups, or as indicated, via 2-way ANOVA.