Figure 9. Altered levels of MBP, PSD95, and EphA4 in postmortem brain tissue from patients with MDD.

(A) Representative Western blot images of MBP protein extracted from postmortem brain tissues donated by patients with MDD versus unaffected controls. (B) Densitometric analysis of MBP protein levels (t₂₈ = 2.102). (C) Representative Western blot images of PSD95 protein extracted from postmortem brain tissues donated by patients with MDD versus unaffected control individuals. (D) Densitometric analysis of PSD95 protein levels (t₂₈ = 2.171). (E) Representative Western blot images of EphA4 protein extracted from postmortem brain tissues donated by patients with MDD versus unaffected control individuals. (F) Densitometric analysis of EphA4 protein levels (t₂₈ = 2.577). α-Tubulin was used as a loading control for all blots in this figure and n = 15 for all analyses. Data are shown as the mean ± SEM. *P < 0.05, by unpaired Student’s t test.