Table 3.

Economic Model Assumptions

Section of Model	Assumption	Source
Failure rate of first-line ATD	Approximately 5% of patients will fail to achieve remission with ATD during first-line therapy, requiring an alternative therapy	Expert opinion
ATDs including PTU	Have similar effectiveness, side effect profile and cost	Expert opinion
Choice of therapy after failure of first dose of RAI	Further doses of RAI given, rather than switching to other therapy.	Most common practice in Ethiopia
Side effect of ATD and RAI	Does not have significant cost implications and not considered.	[11]
Hypothyroidism after RAI and ATDs	Hypothyroidism is considered as treatment success along with Euthyroidism.	[12,13]