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. Author manuscript; available in PMC: 2022 Apr 15.
Published in final edited form as: Prog Cardiovasc Dis. 2020 Mar 25;63(3):263–270. doi: 10.1016/j.pcad.2020.03.010

Table 3.

Proposed criteria for Postural Orthostatic Tachycardia Syndrome (POTS).

Reproducible orthostatic tachycardia (HR rise ≥ 30 bpm > age 19 and ≥ 40 bpm age ≤ 19) with symptoms of orthostatic intolerance
1. A clear definition of orthostatic change in position and time in each position
2. Orthostatic tachycardia within 3–10 min of standing and/or on a tilt table test
3. No evidence for orthostatic hypotension at any time with standing
4. A chronic condition present for at least six months
5. No other explainable cause for orthostatic tachycardia or tachycardia
6. Symptoms of orthostatic intolerance that include postural chest pain, exertional dyspnea, dependent acrocyanosis, dizziness, lightheadedness with associated heart rate response abnormalities.
7. Orthostatic symptoms disappear when supine
8. Extra orthostatic symptoms - chronic fatigue, “brain fog”
9. Other autonomic symptoms – bloating, constipation, sweating abnormalities
10. Syncope is not a criterion
11. Symptoms alone do not make the diagnosis
12. “Secondary” orthostatic tachycardia is not POTS