Table 3.
Demographic and clinical characteristics of patients with COVID-19 admitted to Spanish ICUs.
| All patients, n | 6102 |
| Age (years) | 63 [54-71] |
| Sex (male) | 4290 (70.3) |
| BMI | 28.8 [26.0-32.3] |
| Comorbidities (No. with data) | |
| Hypertension | 3075 (50.4) |
| Diabetes mellitus | 1507 (24.7) |
| Chronic cardiovascular disease | 793 (13.0) |
| Chronic pulmonary disease | 622 (10.2) |
| Chronic kidney disease | 439 (7.2) |
| Disease chronology from symptoms onset | |
| To hospital admission (days) | 7 [5-9] |
| To ICU admission (days) | 9 [7-12] |
| To IMV start (days) | 10 [7-13] |
| Symptoms at hospital admission | |
| Fever | 5123 (82.9) |
| Dry cough | 3740 (61.3) |
| Productive cough | 790 (12.9) |
| Shortness of breath | 4432 (72.6) |
| Anosmia | 442 (7.2) |
| Headache | 834 (13.7) |
| Myalgia | 1646 (27.0) |
| Diarrhea | 1320 (21.6) |
| Severity scores at ICU admission | |
| SOFA | 5 [4-7] |
| APACHE II | 12 [9-16] |
| Vital signs at ICU admission | |
| Temperature (°C) | 36.8 [36.0-37.5] |
| Mean arterial pressure (mmHg) | 88 [75-100] |
| Respiratory rate (bpm) | 25 [21-31] |
| Blood gases and laboratory parameters at ICU admission | |
| PaO2/FiO2 (mmHg) | 112.5 [80.6-163.3] |
| PaCO2 (mmHg) | 39.0 [34.0-47.0] |
| pH | 7.41 [7.34-7.46] |
| Lymphocyte count (×109/L) | 0.69 [0.47-0.99] |
| D-dimer (ng/mL) | 1000.0 [518.0-2334.75] |
| C-reactive protein (mg/L) | 128.0 [61.5-220.0] |
| Ferritin (pg/mL) | 1142.0 [605.7-1880.3] |
| IL-6 (pg/mL) | 86.6 [31.6-222.3] |
| Interventions | |
| IMV | 4638 (76.0) |
| Prone position | 3667 (60.1) |
| Tracheostomy | 1812 (29.7) |
| ECMO | 164 (2.7) |
| Renal replacement therapy | 549 (9.7) |
| Complications | |
| ARDS | 4792 (78.6) |
| Bacterial pneumonia | 1861 (30.5) |
| Pulmonary embolism | 568 (9.3) |
| Coagulation disorder | 1458 (23.9) |
| Acute renal injury | 1953 (32.0) |
| Liver disfunction | 1825 (29.9) |
| Outcomes | |
| ICU length (days) | 13 [7-27] |
| IMV length (days) | 15 [8-27] |
| Hospital length (days) | 23 [14-40] |
| In-hospital mortality | 1911 (31.4) |
APACHE-II: Acute Physiology and Chronic Health Evaluation; ARDS: acute respiratory distress syndrome; BMI: body mass index; ECMO: extracorporeal membrane oxygenation; ICU: intensive care unit; IL-6: interleukin-6; IMV: invasive mechanical ventilation; SOFA: Sequential Organ Failure Assessment.
Data are expressed as n (%) or median [interquartile range].