Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 1;13:887330. doi: 10.3389/fphar.2022.887330

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhang, Zheng, Luo, Lin, Que, Wang, Huang, Yang, Ye and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

lncRNA-mRNA co-expression networks and real-time quantitative PCR validation. (A) Four verified co-expression networks of mRNAs and their associated lncRNAs. The blue dots represent mRNAs and red dots represent their correlated lncRNAs. There were 309 positive interactions (linked with continuous lines) and 66 negative interactions (linked with dotted lines). The absolute value of correlation coefficients of all the directly linked pairs exceeded 0.990. (B) Venn diagram illustrating the intersections of lncRNAs with Pearson correlation coefficients equal to or higher than 0.992, using 4-way Venn Diagram Generator. The common intersection result is upregulated lncRNA XR-349460, NR-133666 and ENSRNOT00000076920. (C) The qRT-PCR validation of the three selected lncRNA. Results were similar to that of lncRNA microarray.