Table 3.
The summary of the parameters utilized to describe the reversible aggregations formations for SARS-CoV-2 Omicron spike protein for the various gold colloidal sizes. In below, those parameters reported for SARS-CoV-2 Alpha spike proteins9 are reproduced as a comparison. A comparison of the parameters D and E for Omicron and Alpha are shown in Fig. 6a and b.
| Omicron | ||||||
|---|---|---|---|---|---|---|
| d (nm) | A (nm) | B (nm) | C (nm) | D (nm) | E | <R2 > |
| 10 | 582(2) | 2(1) | 0.8(2) | – | – | 0.91415 |
| 15 | 587(2) | 0.03(3) | 2.5(4) | – | – | 0.988 |
| 20 | 575(4) | 13(3) | 0.68(6) | 2(2) | 0.03(11) | 0.93464 |
| 30 | 581(5) | 27(5) | 0.04(4) | 7(2) | -0.04(2) | 0.97604 |
| 40 | 622(4) | 5(3) | 0.8(1) | 4(2) | 0.04(6) | 0.94479 |
| 50 | 629(4) | 5(3) | 0.6(2) | 15(2) | 0.08(2) | 0.94302 |
| 60 | 560(14) | 70(16) | 0.14(6) | 0.3(16) | -0.2(3) | 0.77487 |
| 80 | 581(2) | 62(3) | 0.153(9) | 2(1) | 0.005(41) | 0.99323 |
| 100 | 621(5) | 22(5) | 0.45(6) | 8(3) | 0.10(6) | 0.97158 |
| Alpha | ||||||
| d (nm) | A (nm) | B (nm) | C (nm) | D (nm) | E | <R2 > |
| 10 | 580(1) | 0.7(5) | 1.1(2) | 1.2(9) | 0.002(70) | 0.929 |
| 15 | 581(1) | 0.16(6) | 1.8(1) | 1.0(5) | -0.05(4) | 0.988 |
| 20 | 583(3) | 11(2) | 0.72(5) | 3(1) | 0.008(33) | 0.992 |
| 30 | 593(4) | 15(3) | 0.48(6) | 21(2) | 0.09(2) | 0.982 |
| 40 | 596(10) | 6(6) | 0.9(3) | 30(7) | 0.06(3) | 0.898 |
| 50 | 590(12) | 8(7) | 0.8(3) | 26(7) | 0.05(3) | 0.889 |
| 60 | 574(8) | 11(6) | 0.7(1) | 23(4) | 0.04(2) | 0.948 |
| 80 | 592(5) | 28(4) | 0.45(4) | 19(3) | 0.06(2) | 0.985 |
| 100 | 635(1) | 5.5(8) | 0.70(4) | 8.6(6) | 0.016(7) | 0.995 |