Table 1:

Summary of Demographics for SOPHIA (ITT population)

	Margetuximab plus Chemotherapy (N = 266)	Trastuzumab plus Chemotherapy (N = 270)	Total (N = 536)
Sex, n (%)
Female	266 (100.0)	267 (98.9)	533 (99.4)
Male	0	3 (1.1)	3 (0.6)
Age (years)
Median	55	56	56
Range	29 – 83	27 – 86	27 – 86
Race, n (%)
White	205 (77.1)	222 (82.2)	427 (79.7)
Black or African American	16 (6.0)	12 (4.4)	28 (5.2)
Asian	20 (7.5)	14 (5.2)	34 (6.3)
American Indian or Alaska Native	0	0	0
Native Hawaiian or Pacific Islander	1 (0.4)	2 (0.7)	3 (0.6)
Other	24 (9.0)	20 (7.4)	44 (8.2)
ECOG
0	149 (56.0)	161 (59.6)	310 (57.8)
1	117 (44.0)	109 (40.4)	226 (42.2)

Source: Margetuximab Assessment Aid submitted to FDA (Study 04 CSR - Table 14.1.5)²⁴