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. 2022 Apr 15;12:6352. doi: 10.1038/s41598-022-09949-5

Table 1.

DFS endpoint characteristics.

N = 88 cohorts (84 unique studies)
Total number of participants included in DFS analysis across all studies 212,191
Total DFS events, all studies 41,604
Total distant DFS events, all studies 23,205
Median number of participants contributing to DFS endpoint (range) 1629 (58a–9366)
Median number of DFS events per study (range) 306 (27–1975)
Median number of distant DFS events per study (range) 184.5 (11–1025)
Median % distant events by study 57.0 (21.1–83.3%)
DFS-type endpoint
iDFS 9 (10.2%)
DFS 74 (84.1%)
EFS 5 (5.7%)

aAlthough we excluded studies with less than 100 participants, this study was split into 2 cohorts for the analysis, but the total number of participants in the study was above 100.

This table shows the DFS characteristics of the 88 cohorts included in this analysis. DFS disease free survival, iDFS invasive disease free survival, EFS event free survival.