Table 1. Drugs generating photosensitivity 16-20 .
Therapeutic group | Drugs |
Central nervous system (CNS) acting agents |
Neuroleptics: chlorpromazine, thioridazine, trifluoperazine, fluphenazine, flupentixol, thiothixene, chlorprothixene, haloperidol, clozapine Antidepressants: amitriptyline, imipramine, fluoxetine, paroxetine, sertraline, venlafaxine Sedato-hipnotics: diazepam, alprazolam, chlordiazepoxide Antiepileptics: carbamazepine, lamotrigine, phenytoin |
Cardiovascular system acting agents |
Antiarrhythmics: amiodarone, quinidine Ca2+ channel blockers: nifedipine, amlodipine, diltiazem ACE inhibitors: ramipril, quinapril, enalapril Diuretics: furosemide, hydrochlorothiazide Statins: simvastatin, atorvastatin, pravastatin |
Non-steroidal anti-inflammatory drugs | Ketoprofen, ibuprofen, naproxen, diclofenac, indomethacin, phenylbutazone |
Antidiabetics | Glipizide, glyburide, glibenclamide, glimepiride |
Antihistamines | Cyproheptadine, diphenhydramine, dimetindene, loratadine, cetirizine |
Antipathogenic agents |
Antibacterial agents: fluoroquinolones, tetracyclines, sulphonamides and trimethoprim, cefotaxime, ceftazidime, metronidazole Antifungals: voriconazole, itraconazole, terconazole, flucytosine, griseofulvin, bifonazole, fluconazole Anti-malaria agents: quinine, chloroquine, hydroxychloroquine Antivirals: efavirenz, saquinavir, acyclovir, ritonavir, zalcitabine |
Antineoplastic agents | Vandetanib, imatinib, fluorouracil and structurally related substances (tegafur, capecitabin), paclitaxel, methotrexate, vinblastine, dacarbazine |
Systemic dermatologic agents | Isotretinoin, methoxsalen, acitretin |
Herbs | Hypericin, fluorocoumarin |