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. 2022 Apr 15;5(4):e227503. doi: 10.1001/jamanetworkopen.2022.7503

Table. Baseline Characteristics of the Offspring According to Prenatal Exposure to Maternal Autoimmune Diseases.

Characteristics Maternal autoimmune disease, No. (%)
Exposed offspring (n = 50 863) Unexposed offspring (n = 2 203 371)
Sex
Female 24 997 (49.15) 1 072 255 (48.66)
Male 25 863 (50.85) 1 130 119 (51.29)
Missing 3 (0.01) 997 (0.05)
Calendar year of birth
1978-1985 3187 (6.27) 424 492 (19.27)
1986-1994 6232 (12.25) 538 798 (24.45)
1995-2005 16 391 (32.23) 679 775 (30.85)
2006-2016 25 053 (49.26) 560 306 (25.43)
Gestational age at birth, wk
<37 5161 (10.15) 94 899 (4.31)
≥37 44 991 (88.46) 2 028 343 (92.06)
Missing 711 (1.40) 80 129 (3.64)
Maternal parity
1 21 193 (41.67) 986 635 (44.78)
2 19 583 (38.50) 818 434 (37.14)
≥3 10 087 (19.83) 398 302 (18.08)
Maternal age at childbirth, y
<20 332 (0.65) 39 822 (1.81)
20-34 38 590 (75.87) 1 839 428 (83.48)
≥35 11 941 (23.48) 324 121 (14.71)
Maternal educational level at childbirth, y
0-9 10 902 (21.43) 595 282 (27.02)
10-14 22 309 (43.86) 951 005 (43.16)
≥15 17 136 (33.69) 613 715 (27.85)
Missing 516 (1.01) 43 369 (1.97)
Maternal cohabitation at childbirth
Yes 27 003 (53.09) 1 214 548 (55.12)
No 23 851 (46.89) 986 215 (44.76)
Missing 9 (0.02) 2608 (0.12)
Maternal residence at childbirth
Copenhagen 6219 (12.23) 244 865 (11.11)
City with ≥100 000 inhabitants 7110 (13.98) 280 727 (12.74)
Other 37 534 (73.79) 1 677 779 (76.15)
Maternal country of birth
Denmark 46 124 (90.68) 1 955 104 (88.73)
Other 4712 (9.26) 243 512 (11.05)
Missing 27 (0.05) 4755 (0.22)