Table 1.
Cohort characteristics
| Characteristic | Acute MI group (N = 49) | Stable CAD group (N = 15) |
P value |
|---|---|---|---|
| Age (mean ± SD) years | 58.59 ± 14.42 | 61.33 ± 8.86 | 0.49 |
| Males (%) | 65.3 | 53.3 | 0.59 |
| Caucasian race (%) | 77.6 | 93.3 | 0.32 |
| Current smoker (%) | 53.1 | 20.0 | 0.05 |
| Currently consumes alcohol (%) | 32.7 | 46.7 | 0.50 |
| History of dyslipidemia (%) | 46.9 | 86.7 | 0.047 |
| History of diabetes mellitus (%) | 10.2 | 40.0 | 0.022 |
| History of hypertension (%) | 61.2 | 93.3 | 0.042 |
| History of atherosclerosis (%) (MI, CAD, PCI, CABG) | 30.6 | 93.3 | < 0.001 |
| History of congestive heart failure (%) | 8.2 | 6.7 | 1.00 |
| HR at time of presentation (mean ± SD) | 84.90 ± 24.98 | 65.87 ± 9.59 | 0.006 |
| MAP at time of presentation (mean ± SD) | 102.77 ± 24.72 | 91.36 ± 14.29 | 0.10 |
| BMI at time of presentation (mean ± SD) | 27.54 ± 7.24 | 33 ± 7.08 | 0.013 |
| Baseline troponin (mean ± SD, range) mg/dL | 5.59 ± 10.83 | 0.01 ± 0.00 | 0.05 |
| Peak troponin (mean ± SD, range) | 33.53 ± 37.94 | 0.01 ± 0.00 | 0.002 |
| Glucose at baseline (mean ± SD, range) | 142.14 ± 56.46 | 131.60 ± 30.61 | 0.493 |
| Creatinine at baseline (mean ± SD, range) | 1.13 ± 0.79 | 0.92 ± 0.17 | 0.32 |
| ST elevation on EKG at baseline (%) | 63.3 | 0.0 | < 0.001 |
| At least one vessel with ≥ 50% coronary stenosis on enrollment angiogram (%) | 73.5 | 40.0 | 0.03 |
| Aspirin use at time of enrollment (%) | 34.7 | 100 | < 0.001 |
| Clopidogrel use at enrollment (%) | 10.2 | 66.7 | < 0.001 |
| Statin use at time of enrollment (%) | 32.7 | 80 | 0.003 |
| ACE-I/ARB use at time of enrollment (%) | 28.6 | 66.7 | 0.018 |
| Beta blocker use at time of enrollment (%) | 24.5 | 66.7 | 0.007 |
| Calcium channel blocker use at time of enrollment (%) | 14.3 | 53.3 | 0.006 |
| NSAIDs use at time of enrollment (%) | 38.8 | 0 | 0.011 |
Bold values indicate statistical significance (p < 0.05)
ACE-I Angiotensin converting enzyme inhibitor, ARB Angiotensin II receptor blockers, BMI Body Mass Index, CABG coronary artery bypass grafting, CAD coronary artery disease, DBP diastolic blood pressure, EKG electrocardiogram, HR heart rate, MAP mean arterial pressure, MI myocardial infarction, NSAIDs nonsteroidal anti-inflammatory drugs, PCI percutaneous coronary intervention, SBP systolic blood pressure, SD standard deviation