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. Author manuscript; available in PMC: 2022 Apr 16.
Published in final edited form as: Mayo Clin Proc. 2022 Feb;97(2):250–260. doi: 10.1016/j.mayocp.2021.08.026

Table 1.

Drugs responsible for 80% of the costs related to rheumatology prescriptions. Drugs are listed in descending mean annual cost per beneficiary in US dollars.

Medication % of costs Total Number of Rheumatologist Prescribers Mean Annual Medication Cost, $ Mean Annual Cost per Beneficiary, $1
rACTH 2.4 156 81,819,665 229,955
Adalimumab 18.1 3872 619,979,397 21,492
Etanercept 21.7 4068 740,776,562 20,728
Infliximab 15.8 1349 539,084,516 15,941
Golimumab 1.9 1124 66,218,740 15,476
Rituximab 1.8 490 108,285,621 15,173
Certolizumab 2.7 1051 91,209,539 13,941
Abatacept 6.8 1936 224,659,322 13,445
Teriparatide 1.9 1596 65,124,565 9,379
Denosumab 2.0 1671 69,004,446 1,268
HCQ 2.4 4664 82,781,282 362
Methotrexate 3.0 4721 103,695,961 358
Prednisone 0.5 4776 15,717,827 42
1

Defined as total drug cost divided by number of beneficiaries for the subset with available beneficiary counts (i.e., physicians with >10 beneficiaries per year)

rACTH, Repository corticotropin; HCQ, hydroxychloroquine