Table 2.
Overall (N = 363) |
Non-clinical FCRI (N = 221) | Clinical FCRIa (N = 142) |
Association | |||
---|---|---|---|---|---|---|
Measurement tools | range | Mean ± SD | Mean ± SD | Mean ± SD | Beta coefficientsb | P-value |
Communication unsatisfactiond | 3–15 | 4.3 ± 1.8 | 4.1 ± 1.8 | 4.6 ± 1.8 | 0.092 | 0.057 |
Care coordinationd | 1–5 | 1.7 ± 0.9 | 1.6 ± 0.8 | 1.9 ± 0.9 | 0.080 | 0.295 |
Functional social support, meanc | 1–8 | 3.0 ± 1.0 | 3.2 ± 1.7 | 2.5 ± 1.5 | -0.190 | < 0.001 |
Confidant support, total | 5–25 | 15.0 ± 3.9 | 16.0 ± 3.6 | 13.4 ± 3.8 | -0.164 | 0.002 |
Affective support, total | 3–15 | 11.2 ± 2.9 | 12.3 ± 2.5 | 9.8 ± 2.7 | -0.201 | < 0.001 |
EQ_VASc | 0–100 | 68.9 ± 16.4 | 70.8 ± 15.7 | 66.6 ± 16.6 | -0.126 | 0.019 |
EORTC QLQ-C30 | ||||||
Global health status/QOLc | 0–100 | 66.1 ± 17.3 | 67.9 ± 16.7 | 63.6 ± 17.4 | -0.159 | 0.003 |
Functional scalesc | ||||||
Physical functioning | 0–100 | 81.7 ± 15.3 | 84.1 ± 14.4 | 78.0 ± 15.2 | -0.175 | 0.001 |
Role functioning | 0–100 | 86.9 ± 18.7 | 89.5 ± 16.7 | 83.2 ± 21.0 | -0.154 | 0.004 |
Emotional functioning | 0–100 | 79.4 ± 18.4 | 84.5 ± 15.7 | 70.9 ± 19.2 | -0.356 | < 0.001 |
Cognitive functioning | 0–100 | 76.8 ± 17.8 | 79.4 ± 16.4 | 72.1 ± 18.3 | -0.204 | < 0.001 |
Social functioning | 0–100 | 80.2 ± 22.8 | 84.7 ± 18.4 | 72.7 ± 26.1 | -0.272 | < 0.001 |
Symptom scalesd | ||||||
Fatigue | 0–100 | 34.9 ± 23.4 | 29.9 ± 21.9 | 43.0 ± 23.4 | 0.243 | < 0.001 |
Nausea and vomiting | 0–100 | 12.8 ± 17.0 | 10.6 ± 17.1 | 16.8 ± 17.8 | 0.150 | 0.004 |
Pain | 0–100 | 14.2 ± 18.7 | 11.4 ± 17.9 | 18.6 ± 19.4 | 0.183 | 0.001 |
Dyspnea | 0–100 | 16.0 ± 21.7 | 13.0 ± 19.7 | 20.4 ± 23.1 | 0.154 | 0.004 |
Insomnia | 0–100 | 27.3 ± 31.6 | 23.9 ± 31.4 | 32.2 ± 30.6 | 0.135 | 0.011 |
Appetite loss | 0–100 | 13.9 ± 21.5 | 11.9 ± 21.2 | 17.1 ± 22.4 | 0.107 | 0.047 |
Constipation | 0–100 | 17.5 ± 23.1 | 16.3 ± 22.2 | 19.7 ± 24.8 | 0.060 | 0.264 |
Diarrhea | 0–100 | 31.8 ± 26.4 | 28.7 ± 25.1 | 36.9 ± 27.7 | 0.121 | 0.020 |
Financial difficulties | 0–100 | 18.4 ± 24.7 | 15.5 ± 22.4 | 23.0 ± 27.6 | 0.167 | 0.002 |
Fatigue severity scaled | 1–7 | 2.8 ± 1.7 | 2.4 ± 1.5 | 3.4 ± 1.8 | 0.333 | < 0.001 |
Sleep problemsd | 1–4 | 2.0 ± 1.1 | 1.9 ± 1.1 | 2.1 ± 1.1 | 0.299 | 0.002 |
Anxietyd | 0–18 | 4.7 ± 3.3 | 3.5 ± 2.5 | 6.5 ± 3.5 | 0.443 | < 0.001 |
Depressiond | 0–18 | 8.0 ± 3.6 | 7.4 ± 3.5 | 8.9 ± 3.6 | 0.207 | < 0.001 |
Data were presented as mean value ± standard deviation
aThe score of FCRI short form (FCRI severity subscale) was ≥ 13
bEstimated using linear regression analysis after adjusting for age, sex, cancer stage, Carlson’s Comorbidity Index, and time since cancer diagnosis. In the analysis, each health-related quality of life and psychosocial factor was put as a dependent variable and the level of FCRI was put as an independent variable.
Significant correlation below Bonferroni cut-off (p < 0.002) are in bold
cHigher score means better health status
dLower score means better health status