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. 2022 Apr 15;41:145. doi: 10.1186/s13046-022-02348-8

Table 1.

Correlation of IL-32 expression level with clinicopathological features in ESCC patients

Variables All cases (N) IL-32 expression level (IHC-score) P valuea, b
Low, N (%) High, N (%)
Age (year)
 < 57 15 9 (16.1) 6 (10.7) 0.905
 >=57 41 22 (39.3) 19 (33.9)
Gender
 Male 41 24 (42.9) 17 (30.4) 0.626
 Female 15 7 (12.5) 8 (14.3)
Tumor location
 Upper 9 8 (14.3) 1 (1.8) 0.087
 Middle 33 16 (28.6) 17 (30.4)
 Lower 14 7 (12.5) 7 (12.5)
Tumor differentiation
 Well 10 8 (14.3) 2 (3.6) 0.159
 Moderate 33 15 (26.8) 18 (32.1)
 Poor 13 7 (12.5) 6 (10.7)
Pathological stage
 IA-IB 9 6 (10.7) 3 (5.4) 0.304
 IIA-IIB 22 14 (25) 8 (14.3)
 IIIA-IIIC 25 11 (19.6) 14 (25)
Tumor stage
 T1-T2 24 13 (23.2) 11 (19.6) 0.265
 T3-T4 32 18 (32.1) 14 (25)
Nodal stage
 N0 27 18 (32.1) 9 (16.1) 0.025*
 N1 21 12 (21.4) 9 (16.1)
 N2-N3 8 1 (1.8) 7 (12.5)

N Number

aχ2 test to compare clinicopathological parameters in IL-32 low-expression group versus high-expression group

bP < 0.05 is compared significant