Table 2.

Sensitivity analyses assessing the effectiveness of three types of SARS-CoV-2 treatments. For each treatment type, effectiveness is assessed at two different values of the basic reproduction number (3 and 6), proportion of the population ever infected at onset of treatment (20% and 50%), treatment coverage (50% and 80%), and treatment efficacy (50% and 80%). Treatment effectiveness is also assessed by combining these values to yield the worst-case scenario and best-case scenario for treatment effectiveness.

	Basic reproduction number		Proportion of the population ever infected at onset of treatment		Treatment coverage		Primary treatment efficacy		Worst scenarioa	Best scenariob
	3.0	6.0	20%	50%	50%	80%	50%	80%	Combination	Combination
Number of treatments needed to avert one severe or critical disease case
Severe and critical infection treatment	2.0	2.0	2.0	2.0	2.0	2.0	2.0	1.3	2.0	1.3
Post-exposure prophylactic treatment	81.4	231.5	48.0	25.6	100.0	81.4	81.4	22.2	183.7	25.1
Pre-exposure prophylactic treatment	46.1	50.8	43.1	47.4	51.3	46.1	46.1	24.4	46.8	30.2

^aCombination of parameter values to yield the worst-case scenario for treatment effectiveness.

^bCombination of parameter values to yield the best-case scenario for treatment effectiveness.