Table 5.
Interaction effects of exposure to TVOCs and PM2.5 on the risks of CHD
| Exposure | N, controls/cases | AORa (95% CI) |
|---|---|---|
| Low TVOC and low PM2.5 | 40/12 | Reference |
| High TVOC and low PM2.5 | 12/15 | 3.70 (0.93–14.65) |
| Low TVOC and high PM2.5 | 17/4 | 0.80 (0.18–3.66) |
| High TVOC and high PM2.5 | 6/13 | 8.99* (2.05–39.41) |
| Cross-product for interaction | 6.99* (1.75–27.85) | |
| RERI on the additive scale | 5.49 (-8.99–19.97) | |
| AP on the additive scale | 0.61 (-0.25–1.47) | |
Low TVOC was defined as a TVOC concentration ≤ 0.30 mg/m3, while high TVOC was defined as a TVOC concentration > 0.30 mg/m3; low PM2.5 was defined as a PM2.5 concentration ≤ 13 µg/m3, while high PM2.5 was defined as a PM2.5 concentration > 13 µg/m3
aAdjusted for maternal and paternal age, maternal and paternal education level, house renovation and ventilation (category), exposure to environmental pollutants near the residence (category), and smoke ventilator usage when cooking. The low-level group served as the referenc
*Adjust p value (Benjamin-Hochberg correction) < 0.05 vs. control