Table 4. Crude and adjusted ORs of factors associated with AKI.
| Explanatory variable | Crude OR a [95% CI] | p-value | Adjusted b OR [95% CI] | p-value |
|---|---|---|---|---|
| Indomethacin use | 2.94 [1.73:5.03] | <0.001 | 2.73 [1.55:4.80] | 0.001 |
| Concomitant drug use c | ||||
| Aminoglycosides | 1.50 [0.72:3.11] | 0.277 | ||
| Corticosteroids | 1.00 [0.06:15.99] | 1.000 | ||
| Furosemide | 2.08 [1.05:4.15] | 0.037 | 1.80 [0.81:3.98] | 0.150 |
| Vancomycin | 0.17 [0.02:1.38] | 0.097 | 0.25 [0.02:2.58] | 0.243 |
| Vasopressors and inotropes | 1.90 [0.88:4.09] | 0.100 | 1.99 [0.77:5.15] | 0.155 |
a
Univariate conditional logistic regression
b
Conditional logistic regression; OR adjusted for covariates i.e. concomitant drug use.
c
Concomitant drug use: aminoglycosides (amikacin or gentamicin); systemic corticosteroids (dexamethasone or hydrocortisone); systemic vasopressors and inotropes (adrenaline, dobutamine, dopamine, milrinone, or noradrenaline).