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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Thorax. 2022 Jan 7;77(5):508–510. doi: 10.1136/thoraxjnl-2021-217693

Table 3.

Association of candidate gene variants with HP

All HP Fibrotic HP Non-fibrotic HP Full model* (fbrotic HP)
CHR Gene SNP OR Adjusted P value OR Adjusted P value OR Adjusted P value OR P value
3 TERC rs2293607 1.31 0.04 1.42 0.03 1.04 0.97 1.37 0.04
4 FAM13A rs2609260 1.35 0.04 1.29 0.19 1.63 0.15 1.29 0.13
5 TERT rs7726159 0.88 0.27 0.82 0.21 1.01 0.97 0.85 0.26
6 DSP rs2076295 1.35 0.02 1.37 0.03 1.31 0.43 1.24 0.10
7 ZKSCAN1 rs6963345 1.22 0.08 1.07 0.60 1.38 0.35 1.17 0.26
10 OBFC1 rs2488000 1.22 0.27 0.87 0.60 2.32 0.02 0.85 0.48
11 MUC5B rs35705950 2.11 1.74E-06 2.32 2.61E-06 1.02 0.97 2.26 3.56E-06
13 ATP11A rs1278769 0.72 0.04 0.81 0.21 0.46 0.06 0.81 0.19
15 IVD rs35700143 0.78 0.04 0.66 0.01 1.17 0.81 0.68 0.01
19 DPP9 rs12610495 0.94 0.56 0.82 0.21 1.01 0.97 0.72 0.03
*

Full model includes all 10 variants in a single logistic regression.

CHR, chromosome; HP, hypersensitivity pneumonitis; SNP, single nucleotide polymorphism.