TABLE 5.
Geometric means of organ culture counts for C. tropicalis FA2542
| Treatment | Survivors/no. in group (%) | Sterilizeda | Mean countb
|
|||
|---|---|---|---|---|---|---|
| Brain | Kidneys | Liver | Lungs | |||
| ABLC (10 mg/kg) | 10/10 (100) | 0 | 70 | 70 | 2 | 0 |
| ABLC (5 mg/kg) | 9/10 (90) | 0 | 1.3 × 102 | 3.8 × 102 | 3 | 0 |
| ABLC (2 mg/kg) | 9/9 (100) | 0 | 3.9 × 102 | 4.7 × 102 | 5 | 0 |
| ABLC (1 mg/kg) | 9/10 (90) | 0 | 9.0 × 102 | 1.9 × 103 | 2.3 × 102 | 0 |
| FLU (250 mg/kg) | 10/10 (100) | 0 | 6 | 8.8 × 103 | 2 | 0 |
| FLU (50 mg/kg) | 8/10 (80) | 0 | 2.0 × 102 | 1.4 × 105 | 60 | 0 |
| FLU (25 mg/kg) | 7/9 (78) | 0 | 1.8 × 102 | 7.9 × 104 | 44 | 0 |
| Agar-glucosec | 3/20 (15) | 0 | 8.8 × 103 | 3.3 × 105 | 4.5 × 104 | 0 |
a
Sterilized, number of mice in which all cultures were negative.
b
All counts are expressed as CFU/ml of organ homogenate.
c
Control groups combined (n = 20).