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IC50 values with standard deviation from 5-day survival assay of MIA-PaCa 2 cells treated with CF10 or F10 after 48h of siRNA knockdown of PARG compared to control scrambled siRNA. P-values indicate differences between siCon and siPARG cells.
| MIA-PaCa 2 IC50 (nM) | siCon | siPARG | p-value |
|---|---|---|---|
| CF10 | 24.54 ± 7.32 | 2.41 ± 0.33 | 0.0064 |
| F10 | 90.14 ± 8.73 | 5.61 ± 0.70 | <0.0001 |
