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. 2022 Apr 16;22:190. doi: 10.1186/s12876-022-02257-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Verification the accuracy of the riskscore and predicted the survival probability of colon cancer patients combined with other clinical characters. A Kaplan–Meier curves between high-risk group and low-risk group by TCGA-COAD data. B The AUC score of the riskscore and other clinical indicators at 1 year in the TCGA-COAD data. C The patients from TCGA are divided into high-risk group and low-risk group based on the riskscore median values. D The distribution of survival time in the high-risk group and low-risk group in the TCGA data. E The expression heatmap of CDKN2A, CMTM8, ILK in the high-risk group and low-risk group in the TCGA data. F Univariate cox regression analysis of age, gender, stage, and riskscore in the TCGA data. Riskscore is significantly associated with the survival of colon cancer. G Multivariate cox regression analysis of age, gender, stage, and riskscore in the TCGA data. Riskscore is an independent prognostic factor for the survival of colon cancer. H Nomogram for the prediction of 1-, 3-, 5-year survival probability in patients with colon cancer