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. 2022 Apr 16;19:95. doi: 10.1186/s12974-022-02449-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 10 — Intrathecal injection of SU16f promotes locomotor function recovery after SCI. A Timeline of the intrathecal injection and the behavioural assessment. B Locomotor function was evaluated by BMS at 0, 3, 7, 14, 21 and 28 dpi. ***P < 0.001 and ****P < 0.0001 vs. Control group by two-way ANOVA, n = 8 animals per group. C Representative images of footprint analysis in the Uninjured, Control and SU16f groups at 28 dpi. The front paws are shown in green dyes, and the hind paws are shown in red dyes. D–F Quantification of the stride length, stride width and paw rotation at 28 dpi. *P < 0.05, ***P < 0.001 and ****P < 0.0001 by one-way ANOVA, n = 8 animals per group