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Efficient knockdown of SHP2 by shRNA lentivirus confirmed by qRT-PCR and immunoblotting. (a) SHP2 mRNA levels in the cell lines. (b) Quantitative study of SHP2 expression using western blots (∗∗∗p < 0.001, ∗∗∗∗p < 0.0001). Experiments were repeated three times with three replicates in each experiment.
