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Lens transparency and optical aberration. (A-D) Progressive increase in lens opacity (left columns) and abnormal distortion aberration (right columns) in the lenses of CP49-KO, filensin-KO, and 2xKO mice compared with age-matched WT lenses. Lenses from adult mice at: (A) 2-months of age; (B) 6-months of age; (C) 9-months of age; (D) 12-months of age.
