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. 2022 Apr 13;14:529–544. doi: 10.2147/IJWH.S354655

Table 3.

Associations Between Self-Reported Menstrual Alterations and Sociodemographic Characteristics, Self-Reported Health, Gynecological Diagnosis, and Use of Hormonal Contraception, Among All Participants, Participants Reporting No History of COVID-19 and Participants Reporting a COVID-19 Diagnosis (N=14,773)

All Participants (N=14,773) No History of COVID-19 (N=11,734) Self-Reported COVID-19 Diagnosis (N=1865)
aOR (95% CI) p value aOR (95% CI) p value aOR (95% CI) p value
Age
 18–25 1.00 1.00 1.00
 26–35 0.85 (0.77–0.95) 0.004 0.84 (0.75–0.95) 0.005 0.91 (0.66–1.25) 0.055
 36–45 0.74 (0.65–0.84) <0.001 0.72 (0.63–0.84) <0.001 0.75 (0.51–1.10) 0.139
 46–55 0.80 (0.68–0.95) 0.012 0.78 (0.65–0.94) 0.010 0.90 (0.55–1.47) 0.675
Country of birth
 Spain 1.00 1.00 1.00
 Other 1.15 (0.97–1.37) 0.109 1.01 (0.79–1.29) 0.939 1.26 (0.78–2.04) 0.346
Administrative situation
 Spanish nationality 1.00 1.00 1.00
 Other administrative situation 1.07 (0.86–1.32) 0.542 1.07 (0.86–1.32) 0.542 0.99 (0.54–1.80) 0.963
Employment situation
 Working full-time/part-time 1.11 (1.01–1.23) 0.037 1.14 (1.02–1.28) 0.022 1.03 (0.76–1.39) 0.857
 Self-employed 1.11 (0.96–1.28) 0.154 1.12 (0.95–1.32) 0.165 1.31 (0.85–2.01) 0.225
 Studying full-time/part-time 1.13 (1.02–1.25) 0.019 1.19 (1.06–1.33) 0.003 1.04 (0.76–1.40) 0.824
 On benefits (unemployment, COVID-19 benefits, retirement and other benefits) 1.12 (0.97–1.28) 0.124 1.18 (1.01–1.38) 0.039 0.83 (0.53–1.28) 0.391
 Unpaid carer/houseworker 1.19 (0.99–1.42) 0.064 1.29 (1.05–1.58) 0.015 0.67 (0.38–1.20) 0.177
Completed education
 Primary education 1.00 1.00 1.00
 Secondary education 1.25 (0.86–1.82) 0.250 1.30 (0.87–1.96) 0.207 0.47 (0.14–1.54) 0.212
 University education 1.34 (0.92–1.96) 0.124 1.46 (0.97–2.18) 0.070 0.43 (0.13–1.41) 0.163
Carer
 No 1.00 1.00 1.00
 Yes 0.82 (0.75–0.91) <0.001 0.83 (0.74–0.93) 0.001 0.76 (0.57–1.03) 0.077
Financial problems <12 months
 Never 1.00 1.00 1.00
 Some/A few times 1.31 (1.21–1.42) <0.001 1.33 (1.22–1.45) <0.001 1.29 (1.03–1.61) 0.014
 Always/Many times 1.67 (1.49–1.86) <0.001 1.68 (1.48–1.90) <0.001 1.53 (1.09–2.14) 0.016
Self-perceived health
 Excellent 1.00 1.00 1.00
 Very good 1.15 (0.99–1.33) 0.061 1.11 (0.94–1.30) 0.214 1.48 (0.94–2.33) 0.094
 Good 1.41 (1.22–1.63) <0.001 1.35 (1.15–1.58) <0.001 1.64 (1.04–2.6) 0.033
 Fair 2.00 (1.68–2.40) <0.001 1.88 (1.54–2.30) <0.001 2.75 (1.6–4.72) <0.001
 Poor 2.17 (1.50–3.14) <0.001 2.00 (1.31–3.07) 0.001 3.09 (1.01–9.52) 0.049
Diagnosis
 Endometriosis/adenomyosis 1.12 (0.96–1.30) 0.146 1.05 (0.89–1.24) 0.555 1.51 (0.98–2.32) 0.060
 Myomas 1.17 (1.01–1.35) 0.033 1.17 (1.00–1.37) 0.055 1.03 (0.68–1.56) 0.906
 Polycystic ovary syndrome 1.16 (1.06–1.28) 0.002 1.13 (1.02–1.26) 0.020 1.01 (0.77–1.32) 0.964
 No diagnosis 0.80 (0.74–0.87) <0.001 0.83 (0.75–0.90) <0.001 0.63 (0.49–0.79) <0.001
Use of hormonal contraception
 Never 1.00 1.00 1.00
 Previous use 0.99 (0.91–1.07) 0.723 1.01 (0.92–1.10) 0.897 0.93 (0.73–1.17) 0.517
 Current use 0.52 (0.46–0.58) <0.001 0.55 (0.48–0.62) <0.001 0.40 (0.29–0.54) <0.001
COVID-19
 No COVID-19 1.00
 COVID-19 1.07 (0.98–1.16) 0.118
COVID-19
 No COVID-19 1.00
 Suspected COVID-19 1.15 (1.02–1.30) 0.026
 COVID-19 Diagnosis 1.02 (0.92–1.13) 0.723
COVID-19
 No COVID-19 1.00
 COVID-19 (no Long COVID-19) 0.99 (0.91–1.09) 0.911
 Long COVID-19 1.34 (1.15–1.57) <0.001

Abbreviation: aOR, adjusted odds ratios.