Table 2: Intrasession repeatability assessment of ocular blood flow metrics.
Table reports observed mean ± standard deviation of coefficient of variation (CV, expressed as a percent value) in measurement of various metrics derived from ocular blood flow data at the optic disc, disc vessels, disc perfusion, and fovea regions of interest (ROIs) across multiple cardiac cycles within the same imaging session for healthy (n = 20), glaucoma suspect (n = 16), and glaucoma (n = 10) subjects. Every column of three asterisks (*) indicates that CV of at least one subject group is statistically different (p < 0.05, ANOVA).
VRI: volumetric rise index, VFI: volumetric fall index, TtR: time-to-rise, TtF: time-to-fall, ATI: acceleration time index, BOT: blow-out time
| Intrasession CV (%) |
Ocular Blood Flow Metrics | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROI | Subjects | Dip | Mean | Peak | VRI | VFI | TtR | TtF | Skew | ATI | BOT |
| Optic Disc | Healthy Controls | 2.3 ± 0.9* | 1.8 ± 0.7* | 2.0 ± 0.9 | 8.0 ± 2.9 | 4.5 ± 1.7* | 6.6 ± 2.5 | 3.7 ± 1.3* | 10.2 ± 5.8 | 6.0 ± 2.2 | 3.8 ± 2.1* |
| Glaucoma Suspect | 3.3 ± 1.5* | 2.2 ± 0.9* | 2.2 ± 0.9 | 7.6 ± 2.4 | 4.3 ± 1.4* | 6.6 ± 2.4 | 4.2 ± 1.3* | 10.6 ± 3.2 | 6.0 ± 2.0 | 4.8 ± 1.6* | |
| Glaucoma | 4.6 ± 2.7* | 2.7 ± 0.9* | 2.6 ± 1.2 | 8.6 ± 2.7 | 7.4 ± 4.9* | 7.6 ± 2.6 | 7.0 ± 6.3* | 15.5 ± 9.0 | 9.0 ± 5.7 | 6.4 ± 3.3* | |
| Disc Vessel | Healthy Controls | 2.2 ± 0.8* | 1.6 ± 0.7* | 1.8 ± 0.8 | 7.9 ± 2.8 | 4.4 ± 1.6* | 6.6 ± 2.5 | 3.7 ± 1.3* | 13.3 ± 10 | 6.0 ± 2.2 | 4.6 ± 3.0 |
| Glaucoma Suspect | 3.5 ± 1.7* | 2.2 ± 1.0* | 2.0 ± 1.1 | 7.5 ± 2.4 | 4.3 ± 1.5* | 6.6 ± 2.4 | 4.2 ± 1.3* | 15.7 ± 8.3 | 6.0 ± 2.0 | 6.4 ± 3.0 | |
| Glaucoma | 4.6 ± 2.8* | 2.6 ± 1.0* | 2.5 ± 1.1 | 8.7 ± 2.7 | 7.4 ± 5.1* | 7.6 ± 2.6 | 7.0 ± 6.3* | 17.9 ± 11.7 | 9.0 ± 5.7 | 7.6 ± 3.7 | |
| Disc Perfusion | Healthy Controls | 2.9 ± 1.0* | 2.2 ± 0.8* | 2.5 ± 1.0 | 8.3 ± 3.0 | 4.7 ± 1.7* | 6.6 ± 2.5 | 3.7 ± 1.3* | 10.1 ± 5.7 | 6.0 ± 2.2 | 3.8 ± 2.1* |
| Glaucoma Suspect | 4.2 ± 1.6* | 2.7 ± 0.8* | 2.8 ± 0.9 | 7.9 ± 2.9 | 4.6 ± 1.3* | 6.6 ± 2.4 | 4.2 ± 1.3* | 10.8 ± 4.7 | 6.0 ± 2.0 | 5.2 ± 1.8* | |
| Glaucoma | 5.3 ± 2.8* | 3.0 ± 0.9* | 2.9 ± 1.3 | 8.9 ± 3.0 | 7.3 ± 4.7* | 7.6 ± 2.6 | 7.0 ± 6.3* | 13.8 ± 7.5 | 9.0 ± 5.7 | 6.5 ± 3.1* | |
| Fovea | Healthy Controls | 2.2 ± 0.8 | 1.6 ± 0.6 | 1.7 ± 0.7* | 8.4 ± 3.3 | 5.0 ± 2.4 | 7.3 ± 3.2 | 4.3 ± 2.2 | 13.3 ± 7.0 | 7.3 ± 3.4 | 4.1 ± 1.5* |
| Glaucoma Suspect | 2.5 ± 1.4 | 1.9 ± 0.7 | 2.3 ± 0.8* | 8.4 ± 2.1 | 5.5 ± 2.5 | 7.2 ± 2.0 | 5.1 ± 3.1 | 20.4 ± 11.5 | 7.0 ± 2.0 | 7.9 ± 3.4* | |
| Glaucoma | 3.4 ± 2.6 | 2.3 ± 1.0 | 2.9 ± 1.3* | 9.0 ± 4.2 | 6.7 ± 6.9 | 6.4 ± 3.5 | 5.9 ± 7.7 | 13.1 ± 7.4 | 7.7 ± 3.8 | 7.4 ± 2.5* | |