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. 2022 Apr 4;13:859380. doi: 10.3389/fimmu.2022.859380

Table 1.

Characteristics of included studies in the network meta-analysis.

Study Study design Sample size Ratio of M/F Biopsy class Follow-up Treatments drugs Study quality
Gul et al. (6), Pakistan RCT 28 All female III, IV, V 24 weeks MMF vs. CYC 3
Appel et al. (23), USA RCT 370 1:1.5 III, IV, V 24 weeks MMF vs. CYC 3
Wang et al. (7), China PC 40 1:4.0 III, IV, V 12 months TAC vs. CYC 7
Yap et al. (24), China RCT 16 1:1.7 V 24 months MMF vs. TAC 3
Goswami et al. (25), India CT 83 1:17.1 III, IV, V 6 months MMF vs. RTX 7
Basu et al. (14), India RC 42 1:1.1 IV, V 36 months RTX vs. MMF vs. CYC 4
Sundel et al. (26), UK RCT 346 1:5.7 III, IV, V 24 weeks MMF vs. CYC 6
Wang et al. (28), China RCT 20 NA IV 6 months MMF vs. CYC 3
Lau et al. (29), USA RT 13 1:12 III 6 months MMF vs. CYC 5
El-Shafey et al. (30), Egypt RCT 47 1:22.5 III, IV 24 weeks MMF vs. CYC 3
Sedhain et al. (31), Nepal RCT 42 1:7.4 III, IV, V 24 weeks MMF vs. CYC 3
Feng et al. (32), China RCT 53 1:7.6 III, IV, V 24 weeks MMF vs. CYC 5
Mendonca et al. (33), India RCT 37 1:4 III, IV, V 24 weeks MMF vs. CYC 3
Onishi et al. (27), Japan RT 21 All female III, IV, V 24 weeks+ MMF vs. CYC 5
Joo et al. (34), Korea CT 99 1:10 III, IV, V 12 months MMF vs. CYC 7
Ong et al. (35), Malaysia RCT 44 1:5.3 III, IV, V 6 months MMF vs. CYC 5
Moroni et al. (15), Italy CT 34 1:7.5 III, IV, V 12 months RTX vs. MMF vs. CYC 5
Chen et al. (8), China RCT 81 1:5.8 III, IV, V 6 months TAC vs. CYC 5
Mok et al. (36), Hong Kong RCT 150 1:11.5 V 6 months MMF vs. TAC 5

CT, controlled trial; CYC, cyclophosphamide; M/F, male/female; MMF, mycophenolate mofetil; NA, not available; PC, prospective cohort; RC, retrospective cohort; RCT, randomized controlled trial; RTX, rituximab; TAC, tacrolimus.