Table 1.
Study | Study design | Sample size | Ratio of M/F | Biopsy class | Follow-up | Treatments drugs | Study quality |
---|---|---|---|---|---|---|---|
Gul et al. (6), Pakistan | RCT | 28 | All female | III, IV, V | 24 weeks | MMF vs. CYC | 3 |
Appel et al. (23), USA | RCT | 370 | 1:1.5 | III, IV, V | 24 weeks | MMF vs. CYC | 3 |
Wang et al. (7), China | PC | 40 | 1:4.0 | III, IV, V | 12 months | TAC vs. CYC | 7 |
Yap et al. (24), China | RCT | 16 | 1:1.7 | V | 24 months | MMF vs. TAC | 3 |
Goswami et al. (25), India | CT | 83 | 1:17.1 | III, IV, V | 6 months | MMF vs. RTX | 7 |
Basu et al. (14), India | RC | 42 | 1:1.1 | IV, V | 36 months | RTX vs. MMF vs. CYC | 4 |
Sundel et al. (26), UK | RCT | 346 | 1:5.7 | III, IV, V | 24 weeks | MMF vs. CYC | 6 |
Wang et al. (28), China | RCT | 20 | NA | IV | 6 months | MMF vs. CYC | 3 |
Lau et al. (29), USA | RT | 13 | 1:12 | III | 6 months | MMF vs. CYC | 5 |
El-Shafey et al. (30), Egypt | RCT | 47 | 1:22.5 | III, IV | 24 weeks | MMF vs. CYC | 3 |
Sedhain et al. (31), Nepal | RCT | 42 | 1:7.4 | III, IV, V | 24 weeks | MMF vs. CYC | 3 |
Feng et al. (32), China | RCT | 53 | 1:7.6 | III, IV, V | 24 weeks | MMF vs. CYC | 5 |
Mendonca et al. (33), India | RCT | 37 | 1:4 | III, IV, V | 24 weeks | MMF vs. CYC | 3 |
Onishi et al. (27), Japan | RT | 21 | All female | III, IV, V | 24 weeks+ | MMF vs. CYC | 5 |
Joo et al. (34), Korea | CT | 99 | 1:10 | III, IV, V | 12 months | MMF vs. CYC | 7 |
Ong et al. (35), Malaysia | RCT | 44 | 1:5.3 | III, IV, V | 6 months | MMF vs. CYC | 5 |
Moroni et al. (15), Italy | CT | 34 | 1:7.5 | III, IV, V | 12 months | RTX vs. MMF vs. CYC | 5 |
Chen et al. (8), China | RCT | 81 | 1:5.8 | III, IV, V | 6 months | TAC vs. CYC | 5 |
Mok et al. (36), Hong Kong | RCT | 150 | 1:11.5 | V | 6 months | MMF vs. TAC | 5 |
CT, controlled trial; CYC, cyclophosphamide; M/F, male/female; MMF, mycophenolate mofetil; NA, not available; PC, prospective cohort; RC, retrospective cohort; RCT, randomized controlled trial; RTX, rituximab; TAC, tacrolimus.