Table 1.
Demographic and clinical characteristics of study participants.
| Characteristics | HCs | TNs | IRs | PIRs | ||
|---|---|---|---|---|---|---|
| CD4≥350 | 200≤CD4<350 | CD4<200 | ||||
| N (%) | 25 | 66 (34.20) | 71 (36.79) | 56 (29.01) | 49 | 21 |
| Sex (M/F) | 24/1 | 64/2 | 68/3 | 56/0 | 48/1 | 21/0 |
| Age (mean, years) | 34 ± 7 | 32 ± 10 | 31 ± 7 | 35 ± 8 | 36 ± 6 | 39 ± 7 |
| CD4 count (cells/mm3), median (IQR) | – | 456 (408-529) | 281 (244-312) | 83 (33-146) | 628 (560-743) | 271 (229-328) |
| CD8 count (cells/mm3), median (IQR) | – | 1085 (796-1401) | 1017 (727-1267) | 729 (547-904) | 788 (656-1009) | 691 (600-790) |
| CD4/CD8 ratio, median (IQR) | – | 0.43 (0.31-0.61) | 0.28 (0.22-0.37) | 0.11 (0.05-0.17) | 0.77 (0.64-1.06) | 0.43 (0.36-0.49) |
| HIV RNA viral load (copies/mL), median (IQR) | – | 11091 (4239-29660) |
35908 (10658-119660) |
82353 (26229-211286) |
<LDL | <LDL |
HC, healthy controls; TN, treatment-naive HIV-1-infected patients; IR, immunological responders; PIR, poor immunological responders; M, male; F, female; LDL, lower detection limit. TNs are divided into three subgroups according to blood CD4+ T cell count.