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. 2022 Apr 4;13:883445. doi: 10.3389/fphar.2022.883445

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Copyright © 2022 Zhou, Wang, Zhang, Chen, Zhu, Jiang, Jiang, Zhao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The miR-320a expression levels are inhibited in DDP resistant CC cells. (A) The miR-320a expressions in para-cancer and CC tissues were determined by qRT-PCR analysis. (B) The miR-320a expressions in DDP sensitive clinical CC tissues and DDP resistant clinical CC tissues were determined by qRT-PCR analysis. (C) The overall survival of miR-320a high- and low expression patients analyzed by the Kaplan-Meier method. (D) IC50 values of DDP resistant CC cell line Hela/DDP and Caski/DDP were verified by MTT assay. (E) The miR-320a expressions of DDP sensitive or resistant CC cell lines Hela and Caski were measured by qRT-PCR. ***, p < 0.001 vs. Control group.