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. 2022 Apr 4;13:883445. doi: 10.3389/fphar.2022.883445

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Copyright © 2022 Zhou, Wang, Zhang, Chen, Zhu, Jiang, Jiang, Zhao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Engineered miR-320a exosomes can be effectively up-taken by Hela/DDP and Caski/DDP cells. (A) The uptake of engineered miR-320a exosomes by Hela/DDP and Caski/DDP was confirmed by laser confocal microscopy. (B) The miR-320a expression in Hela/DDP and Caski/DDP cells after internalizing the engineered miR-320a exosomes was determined by qRT-PCR. ***, p < 0.001 vs. PBS group.