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. 2022 Apr 4;13:857727. doi: 10.3389/fimmu.2022.857727

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Copyright © 2022 Li, Teng, Jiang, Zhang, Luo, Liao and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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YTHDF1 regulates M2 macrophage polarization and suppresses the secretion of inflammatory cytokines in THP-1 cells infected with TP. (A, B) Flow cytometry profile of the expression of M1 and M2 markers (CD86 and CD206) in THP-1 cells infected with TP. (C-D) The concentrations of inflammatory cytokines (TNF-α and IL-1β) in the supernatants of THP-1 cells treated with TP. Data are shown as the mean ± S.D. **P < 0.01, ***P < 0.001,****P < 0.0001.