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. 2022 Apr 4;13:857727. doi: 10.3389/fimmu.2022.857727

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Copyright © 2022 Li, Teng, Jiang, Zhang, Luo, Liao and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SOCS3 may be the target of the m6A reader YTHDF1 in TP-infected macrophages. (A) KEGG pathway analysis of biological processes associated with inflammation and infection in the RNA-seq dataset. (B) Heat map of the top 15 significantly upregulated mRNAs in TP-infected macrophages compared with control cells. (C) The association of binding and perturbation between YTHDF1 and SOCS3 was predicted by m6A2Target. (D) The potential m6A sites on SOCS3 mRNA were analyzed by m6Avar.