Table 3.
Logistic regression analysis (univariate) for current regimen and outcome variables
| Variable | VL suppression | LTFU | ||||||
| OR (95% CI) | P value | Adjusted OR (aOR) | P value | OR (95% CI) | P value | aOR | P value | |
| Current regimen | ||||||||
| First-line regimen | 1 | – | 1 | – | 1 | – | 1 | – |
| Second-line regimen | 0.37 (0.35 to 0.40) | <0.001 | 0.26 (0.23–0.28) | <0.001 | 0.82 (0.78 to 0.87) | <0.001 | 1.21 (1.09–1.35) | <0.001 |
| Regimen combination | ||||||||
| d4t/3TC+EFV | 1 | – | 1 | 1 | – | 1 | – | |
| TDF/3TC/EFV | 1.06 (0.97 to 1.16) | 0.220 | 1.24 (1.10–1.40) | 0.797 | 1.14 (1.09 to 1.19) | <0.001 | 0.14 (0.12–0.15) | <0.001 |
| TDF/FTC/EFV (FDC) | 0.83 (0.77 to 0.90) | <0.001 | 1.42 (1.26–1.59) | <0.001 | 0.83 (0.80 to 0.86) | <0.001 | 0.017 (0.015–0.019) | <0.001 |
| Level of care | ||||||||
| Hospital | 1 | 1 | 1 | 1 | – | |||
| CHC | 1.91 (1.79 to 2.04) | <0.001 | 2.20 (2.02–2.39) | <0.001 | 1.27 (1.22 to 1.31) | <0.001 | 1.14 (1.07–1.21) | <0.001 |
| PHC | 1.22 (1.14 to 1.30) | <0.001 | 1.15 (1.05–1.25) | 0.001 | 1.20 (1.16 to 1.25) | <0.001 | 1.51 (1.42–1.60) | <0.001 |
Bold p values denote statistical significance at the p≤0.05 level. Analysis adjusted for: CD4 at baseline or CD4 at ART initiation and duration on ART.
ART, antiretroviral therapy; CHC, community health centre; d4T, stavudine; EFV, efavirenz; FDC, fixed-dose combination; FTC, emtricitabine; LTFU, lost to follow-up; PHC, primary healthcare clinic; 3TC, lamivudine; TDF, tenofovir; VL, viral load.