Table 3.
Effect of CAMP-siRNA transfection on cytokine production in MAP-infected macrophages.
| Infection and Treatment | TNF-α ± SD | IL-1β ± SD | IL-10 ± SD |
|---|---|---|---|
| (pg/mL) | (pg/mL) | (pg/mL) | |
| Control (No Infection) | 60.52 ± 1.75 | 56.13 ± 1.81 | 125.65 ± 6.11 |
| CAMP-siRNA | 69.07 ± 3.65 | 61.91 ± 2.63 | 120.46 ± 3.97 |
| Control (MAP W/O Treatment) | 173.12 ± 4.73 | 163.87 ± 5.72 | 69.18 ± 3.69 |
| MAP + CAMP-siRNA | 182.67 ± 3.18 | 173.75 ± 4.57 | 75.62 ± 5.26 |
| MAP + CAMP-siRNA + 1,25(OH)2D3 | 144.18 ± 4.03 | 132.86 ± 5.76 | 80.19 ± 2.55 |
| MAP + 1,25(OH)2D3 | 81.66 ± 2.79* | 74.39 ± 3.72* | 105.28 ± 4.58* |
*Indicates P-value of less than 0.05.