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. 2022 Apr 4;14:727805. doi: 10.3389/fnagi.2022.727805

TABLE 3.

DE circRNAs and miRNAs in ceRNA networks under anesthesia/surgery conditions.

circRNA log2Fold Change P-value Up/down regulation circRNA-miRNA
mm9_circ_006949 1.08 0.0449 Up mmu-miR-615-3p
mm9_circ_007155 1.24 0.0497 Up mmu-miR-296-5p
mm9_circ_010522 1.30 0.0466 Up mmu-miR-298-5p
mm9_circ_013251 1.28 0.0489 Up mmu-miR-1966-3p
mm9_circ_014796 1.19 0.0350 Up mmu-miR-298-5p
mm9_circ_016411 1.21 0.0216 Up mmu-miR-615-3p
mm9_circ_018802 1.24 0.0459 Up mmu-miR-1264-5p
mm9_circ_009789 1.98 0.0003 Up mmu-miR-298-5p
mm9_circ_008009 1.48 0.0316 Up mmu-miR-298-5p
mm9_circ_004229 1.52 0.0109 Up mmu-miR-298-3p, mmu-miR-298-5p
mm9_circ_007503 1.31 0.0042 Up mmu-miR-298-5p, mmu-miR-615-3p
mm9_circ_011555 1.50 0.0149 Up mmu-miR-122-5p, mmu-miR-615-3p
mm9_circ_003736 –2.46 2.93E-18 Down mmu-miR-18a-3p, mmu-miR-298-5p mmu-miR-615-3p

Up/downregulation represents the circRNA upregulated or downregulated in aging mice under anesthesia/surgery conditions. circRNA-mRNA is the miRNA that was predicted to bind circRNA through seed sequence matching.