Table 3.

Differential Pathways in WGS Analysis Between ANP and IEP Patients

Pathway	Alt_ANP	Ref_ANP	Alt_IEP	Ref_IEP	p value
Complement and coagulation cascades	22	4	9	12	<0.01*
Alanine aspartate and glutamate metabolism	10	16	16	5	0.02*
Apoptosis	18	8	7	14	0.02*
Ppar signaling pathway	15	11	19	2	0.02*
Allograft rejection	8	18	1	20	0.03*
Oxidative phosphorylation	18	8	8	13	0.04*

Notes: Alt_ANP/Alt_IEP the number of patients who occurred mutant bases in this pathway in ANP group/IEP group, Ref_ANP/Ref_IEP the number of patients who consisted with reference bases in this pathway in ANP group/IEP group; *p value <0.05.

Abbreviations: ANP, acute necrotizing pancreatitis; IEP, interstitial edema pancreatitis; WGS, whole genome sequencing.