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. 2022 Apr 4;65(7):5212–5243. doi: 10.1021/acs.jmedchem.1c01897

Table 1. Sequences and Affinity Constants of Peptides Binding to the PDZ Domain of CAL.

peptide sequencea Ki (μM) ref
CFTR10 Thr-Glu-Glu-Glu-Val-Gln-Asp-Thr-Arg-Leu-OH 390 ± 20 (171)
iCAL36 (40) Ala-Asn-Ser-Arg-Trp-Pro-Thr-Ser-Ile-Ile-OH 22.6 ± 8.0 (172)
kCAL01 (41) Ac-Trp-Gln-Val-Thr-Arg-Val-OH 2.3 ± 0.2 (174)
a

Ac = acetyl.