Table 1. Sequences and Affinity Constants of Peptides Binding to the PDZ Domain of CAL.
peptide | sequencea | Ki (μM) | ref |
---|---|---|---|
CFTR10 | Thr-Glu-Glu-Glu-Val-Gln-Asp-Thr-Arg-Leu-OH | 390 ± 20 | (171) |
iCAL36 (40) | Ala-Asn-Ser-Arg-Trp-Pro-Thr-Ser-Ile-Ile-OH | 22.6 ± 8.0 | (172) |
kCAL01 (41) | Ac-Trp-Gln-Val-Thr-Arg-Val-OH | 2.3 ± 0.2 | (174) |
Ac = acetyl.