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Biochemical inhibition of PLD1/2 was determined by immunoprecipitated on plate (IPoP) assay of PLD1/2 from HEK cells.
Cellular assay performed in Calu-1 cells.
Intrinsic Cl (Clint) in rat or human liver microsomes.
Efflux ratio = Papp(B – A)/Papp(A – B) MDCK-MDR1.
