Table 2.
The correlation between the selective gene signature and different types of immune cells
| Cell type | Cell markers | Tumor | Normal | ||
|---|---|---|---|---|---|
| Cor | P | Cor | P | ||
| B cell | CD19|CD38|BLNK | 0.25 | *** | 0.41 | *** |
| Naïve T cell | CCR7|LEF1|TCF7|SELL | 0.43 | *** | 0.4 | *** |
| Effector T cell | CX3CR1|FGFBP2|FCGR3A | 0.3 | *** | 0.0015 | 0.99 |
| Resident memory T cell | CD69|ITGAE|CXCR6|MYADM | 0.44 | *** | 0.52 | *** |
| Th1-like | CXCL13|HAVCR2|IFNG|CXCR3|BHLHE40|CD4 | 0.27 | *** | 0.23 | ** |
| Treg | FOXP3|CCR8|IL2RA | 0.24 | *** | 0.19 | * |
| T cell exhaustion | PDCD1|CTLA4 | 0.26 | *** | 0.32 | *** |
| Macrophage | CD68|CD11b | 0.25 | *** | 0.041 | 0.66 |
| TAM | HLA-G|CD80|CD86 | 0.21 | *** | 0.18 | 0.055 |
| Monocyte | CD14|CD16A | 0.12 | *** | -0.083 | 0.38 |
| NK | XCL1|KIR3DL1|CD7 | 0.22 | *** | 0.092 | 0.33 |
| Neutrophil | CD15|MPO | 0.25 | *** | 0.091 | 0.34 |
| DC | CD1C|CD141 | 0.39 | *** | 0.19 | * |
| Fibroblasts | AIFM2|S100A4 | 0.06 | 0.03 | − 0.26 | *** |
Bold value represents condition which correlation coefficient > 0.3, it means they have significant relevance