Table 3:
Associations of nutrient intakes in childhood with abdominal visceral adipose tissue (VAT) in adolescence.
| Model 1: Unadjusteda (n=302) | Model 2: + Confoundersb (n=294) | Model 3: + Childhood VATc (n=282) | ||||
| A) Energy Partition Models: | ||||||
| Nutrient (kcal/d) | β (95% CI) d | p f | β (95% CI) d | p f | β (95% CI) d | p f |
| Energy | 0.4 (−0.1, 0.9) | 0.07 | 0.1 (−0.3, 0.6) | 0.56 | 0.1 (−0.3, 0.5) | 0.56 |
| Carbohydrates | −0.2 (−1.3, 0.9) | 0.69 | −0.2 (−1.2, 0.8) | 0.70 | −0.2 (−1.0, 0.7) | 0.72 |
| Starch | 0.5 (−2.4, 3.4) | 0.72 | 0.5 (−2.2, 3.2) | 0.73 | 0.3 (−1.9, 2.6) | 0.76 |
| Sugar | −0.5 (−2.0, 1.0) | 0.51 | −0.4 (−1.8, 1.0) | 0.59 | −0.3 (−1.5, 0.9) | 0.66 |
| Protein | 2.6 (−2.2, 7.3) | 0.29 | 2.3 (−2.2, 6.8) | 0.32 | 3.6 (−0.2, 7.4) | 0.07 |
| Animal Protein | 2.8 (−1.5, 7.0) | 0.20 | 2.0 (−2.0, 6.0) | 0.32 | 2.7 (−0.7, 6.1) | 0.12 |
| Total Fat | 1.2 (−0.4, 2.7) | 0.14 | 0.4 (−1.1, 1.8) | 0.63 | 0.1 (−1.1, 1.3) | 0.89 |
| SFA | 0.1 (−4.7, 4.8) | 0.98 | −1.6 (−6.1, 2.9) | 0.50 | −1.3 (−5.0, 2.5) | 0.52 |
| MUFA | 3.0 (−1.3, 7.2) | 0.17 | 1.7 (−2.2, 5.6) | 0.40 | 0.7 (−2.7, 4.0) | 0.69 |
| PUFA | 5.1 (−2.8, 12.9) | 0.20 | 2.8 (−4.6, 10.3) | 0.45 | 1.1 (−5.2, 7.5) | 0.72 |
| B) Nutrient Density Models: | ||||||
| Nutrient (%TEI) | β (95% CI) e | p f | β (95% CI) e | p f | β (95% CI) e | p f |
| Carbohydrates | −1.5 (−3.5, 0.4) | 0.12 | −0.7 (−2.5, 1.1) | 0.43 | −0.6 (−2.1, 0.9) | 0.46 |
| Starch | −0.4 (−3.6, 2.8) | 0.82 | 0.1 (−2.8, 3.1) | 0.93 | 0.2 (−2.3, 2.7) | 0.89 |
| Sugar | −1.3 (−3.3, 0.7) | 0.19 | −0.6 (−2.5, 1.2) | 0.50 | −0.5 (−2.0, 1.1) | 0.54 |
| Protein | 3.0 (−2.5, 8.4) | 0.28 | 2.3 (−2.8, 7.4) | 0.38 | 3.7 (−0.7, 8.0) | 0.10 |
| Animal Protein | 3.0 (−1.5, 7.6) | 0.19 | 2.1 (−2.2, 6.4) | 0.34 | 2.7 (−0.9, 6.3) | 0.14 |
| Total Fat | 1.5 (−0.9, 3.8) | 0.22 | 0.5 (−1.7, 2.6) | 0.67 | 0.1 (−1.8, 1.9) | 0.94 |
| SFA | 0.9 (−4.5, 6.3) | 0.74 | −1.1 (−6.2, 4.0) | 0.66 | −0.9 (−5.2, 3.4) | 0.69 |
| MUFA | 3.3 (−1.5, 8.2) | 0.18 | 1.8 (−2.7, 6.3) | 0.43 | 0.7 (−3.1, 4.5) | 0.71 |
| PUFA | 4.6 (−3.8, 13) | 0.28 | 2.9 (−5.1, 10.9) | 0.48 | 1.0 (−5.8, 7.8) | 0.78 |
| Fiber | −2.1 (−8.4, 4.2) | 0.51 | −4.4 (−10.7, 1.8) | 0.17 | −3.8 (−9.1, 1.6) | 0.17 |
Model 1: adjusted for energy intake from all other nutrients (energy partition models) or TEI (nutrient density models).
Model 2: adjusted for Model 1 covariates plus sex, age, race/ethnicity, household income, pubertal stage, physical activity, BMI category at visit 1, maternal DM exposure, and HEI-2010 total score at visit 1. 8 participants excluded due to missing data for household income (n=1), pubertal stage (n=1), or physical activity (n=6).
Model 3: adjusted for Model 2 covariates plus abdominal VAT in childhood. 12 participants excluded due to missing data for abdominal VAT at visit 1.
Estimated per 100 kcal/d increase in each nutrient.
Estimated per 5% increase in each nutrient (except fiber, per 5 g/1000 kcal increase).
Bolding indicates p<0.05. Asterisk (*) indicates if below Bonferroni-adjusted p<0.017 (0.05/3 outcomes).
Abbreviations: VAT, visceral adipose tissue; TEI, total energy intake; SFA, saturated fat; MUFA, monounsaturated fat; PUFA, polyunsaturated fat.