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. 2022 Apr 4;12:850767. doi: 10.3389/fonc.2022.850767

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Copyright © 2022 Wang, Zhang, Hu and Qian

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CSF-1R^high TAMs affect the immune landscape of colon adenocarcinoma. (A) Associations between CSF-1R expression and tumor microenvironment in COAD. (B) CIBERSORT analysis of the fractions of infiltrated immune cells in the COAD. (C) Heatmap of the partially differentially expressed genes between CSF-1R^low TAMs and CSF-1R^high TAMs. (D) Volcano map of differentially expressed gene between CSF-1R^low TAMs and CSF-1R^high TAMs. In the Volcano, p < 0.05 was set as the cut-off criterion of significant difference.