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. 2022 Apr 15;21:15347354221090221. doi: 10.1177/15347354221090221

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — (A–D) The screening procedure of miRNAs potentially targeting ABCB1 gene. (A) (Volcano map): Expressions of miRNAs regulated by PS-T via microarray (Affymetrix Gene Chip 4.0): 1257 were up-regulated miRNAs, 1259 were down-regulated miRNAs, and 62 were unchanged miRNAs. (B) (Venn diagram): The results of the intersection of the X and Y data set: 5 miRNAs possibly targeting ABCB1 gene were remained (https://bioinfogp.cnb.csic.es/tools/venny/index.html). (C) (Heat map) The differential expressions of 5 screened miRNAs: 5 were up-regulated and 0 was down-regulated. (D) (Bar plot): The differential expressions of 5 screened miRNAs (arranging from high level to low level). (A) and (C) were conducted by using R package version 4.0.