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Necrotic cell extrusion and apoptotic cell efferocytosis in human epithelial cells. Time-lapse fluorescence confocal microscopy showing cells (red) undergoing optoCaspase-1-induced pyroptosis, optoMLKL-induced necroptosis or optoCaspase-8-induced apoptosis in presence of WT neighbors. The upper panels show CellMask (grey) and mCherry (red) signal, bottom panels show DIC and mCherry. Scale bar, 20 µm.
