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. Author manuscript; available in PMC: 2022 Apr 18.
Published in final edited form as: IEEE Trans Biomed Eng. 2022 Mar 18;69(4):1449–1460. doi: 10.1109/TBME.2021.3119280

Fig. 2.

Fig. 2.

ULM acquisition and processing pipeline. A) A reference transducer acquisition was used to estimate a noise equalization profile to correct for depth dependent attenuation. B) A total of 32000 contrast-enhanced IQ data frames were acquired and SVD filtered to generate isolated microbubble data and C) contrast-enhanced power Doppler images. The isolated microbubble data then went into the ULM processing pipeline, which included microbubble separation, microbubble localization, and microbubble pairing and tracking. D) The final super-resolved images were used to quantify the treatment effect in each CAM tumor therapy group.