Table 2:
Demographics (n=14) | |
Age (years) (mean+/−SD) | 9.2 +/−2.4 |
Gender (% male) | 71% |
Epilepsy Features (n=14) | |
Seizure Medication Use | 50% |
Age at First Seizure (years old) (mean+/−SD) | 7.2 +/−2.9y |
Epilepsy Duration (years) (mean+/−SD) | 2.1 +/− 1.4yr |
Lifetime Seizures (% with ≤5; % ≤10; % >10) | 50%; 21%; 29% |
Predominant Spike Side on Diagnostic EEG
(Left/Right/Bilateral) |
14%; 43%; 43% |
Neurocognitive Scores (n=14) | |
IQ (mean, SD) | 103 +/− 13 |
Inattention (n, %) | 5 (42%) |
Language Learning (mean z-score, SD) | −0.14 +/− 1.0 |
Motor Learning (% mean improvement, SD) | 12 +/− 16% |
Excitability Measurements | |
rMT(%MSO) (n=14) (median, IQR) | 98% [77 to 100%] |
Supramaximal rMT(%) (rMT > 100% MSO) |
50% |
N100 Amplitude (uV) (n=12) | −61 +/− 44 |
Plasticity Measurements *** | |
% MEP Change (n=6) (mean, SD) | +37% +/− 52% |
% N100 Change** (n=9) (mean, SD) | −24 +/− 37% |
A negative number indicates that the N100 peak shrinks (approaches zero)
Wilcoxon Rank Sign test showed that the change in motor evoked potential (MEP) and TMS-EEG Evoked Potential (TEP) amplitude were ns (p>0.05).